Current Content
Volume 48 - Number 4
July/August 2022


Treatment Methods for Lyme Disease in Pediatric Patients

Samantha S. Ficon

Identified Problem: Lyme disease is a growing vector transmitted disease among pediatric patients, which if unrecognized or undertreated, can cause multi-body system dysfunction, including chronic pain, arthralgias, myalgias, and neurological consequences. Early recognition and correct treatment are necessary to prevent long-term sequelae, such as neurological, cardiac, and central nervous system complications, and chronic Lyme disease, which is a controversial topic.

Summary of Data Sources: Primary databases used were PubMed and CINAHL, resulting in 20 articles. Search terms included Lyme disease treatment, Lyme disease management, antibiotics for Lyme disease, antimicrobials for Lyme disease, prevention of Lyme disease, diagnosis of Lyme disease, Lyme meningitis, neurological Lyme, cardiac complications with Lyme disease, central nervous system Lyme, chronic Lyme disease, Post-Treatment Lyme Disease Syndrome (PTLDS), symptoms of Lyme disease, and clinical manifestations of Lyme disease. Inclusion criteria were research studies with pediatric patients and articles published in the last 10 years.

Data Synthesis: Research on treatment recommendations for early disseminated Lyme disease in pediatric patients resulted in a general consensus: the use of oral therapy for disseminated Lyme and the use of intravenous therapy for neurological and cardiac manifestations. PTLDS treatment was controversial and underdeveloped.

Conclusions: Prevention methods exist to prevent Lyme disease, and it is important to educate children and caregivers about them. Health care providers need more education and recognition to test and treat or to refer patients. Although appropriate treatment recommendations are available, more research is needed regarding chronic Lyme disease and PTLDS.